בשל "הגנת זכויות יוצרים" מובא להלן קישור לתקציר המאמר. לקריאתו בטקסט מלא, אנא פנה/י לספרייה הרפואית הזמינה לך. 

Periorbital, perioral, and neck wrinkles are one of the most common concerns of aging skin.

We evaluated the efficacy and safety of high-intensity focused ultrasound (HIFU) device with a 5.5-MHz transducer and a 2.0-mm focal depth for improving periorbital, perioral, and neck wrinkles.

A total of 102 participants were enrolled, and 34 each were assigned to the periorbital, perioral, and neck groups.

All subjects were treated with HIFU three times at 2-week intervals at the corresponding treatment site.

Objective measurements and clinical evaluations were performed at 10 and 16 weeks after treatment.