25.09.2024 |
J Haik 1, I Georgiou, N Farber, A Volkov, E Winkler
Affiliation
- 1The Department of Plastic & Reconstructive Surgery, The Chaim Sheba Medical Center, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Case report
A 64-year-old patient underwent an incisional biopsy of a pigmented lesion on his left big toe. Histopathological examination revealed malignant melanoma (MM) and the patient was admitted to our hospital for further assessment and treatment. Physical examination was notable for palpable lymphadenopathy in the left inguinal region, and the involvement of the inguinal lymph nodes was confirmed by positron emission tomography. The patient underwent amputation of the toe and groin lymph node
Discussion
Jeremiah first reported a donor site SCC in 1948, which had appeared nearly 6 months after harvesting a STSG for reconstruction of a laceration scar [2]. Neilson et al. described a case of a STSG donor site SCC that had became evident 3 months after graft harvesting for closure of a remaining soft tissue defect after excision of a SCC elsewhere in the body [3]. Although the histology in that case was suggestive of a primary lesion, the possibility of a blood-borne metastasis could not have been
Summary
The authors present a case of a patient who developed donor site SCC, which became clinically evident 6 weeks after an uneventful routine split-thickness skin graft harvesting procedure. The etiology of the arising malignant lesion in this case remains undetermined, as predisposing factors had not been identified. Although this may represent a very rare complication, regular donor site scar monitoring is recommended for early identification and treatment of such an entity.
PMID: 17869430
DOI: 10.1016/j.burns.2007.06.006